Liposomal Encapsulation Delivers Medications More Efficiently

By Jody Leach


Drugs used to fight disease typically target specific physical systems or organs. Intravenous drips and injections are the most directly effective delivery method, transferring those medications directly to the blood. Orally administered drugs face degradation from the substances that accompany normal digestion. Liposomal encapsulation creates a protective bubble that wards off acids, while encouraging absorption.

Discoveries leading to this process emerged nearly fifty years ago, and have led to the introduction of more controlled methods of administering medications. It is currently important in treating serious medical conditions such as some forms of cancer, treatment-resistant fungal infections, and degenerative vision conditions commonly associated with old age. Standard drug delivery mechanisms still predominate, but encapsulation is proving equally beneficial.
For a medication to pass through the upper digestive tract without being dissolved, it must be protected by a safe and non-toxic barrier. The substance used to encapsulate these drugs is an organic material that closely mimics human cellular walls, making it safer to ingest. After it has been activated by using one of three common processes, small bubbles of liposomes are formed around the tiny grains of medication.

They are microscopic, and permit the medication protected inside to safely reach the bloodstream via the small intestine, where they are directly absorbed. This not only improves the overall therapeutic intent in many cases, but can also reduce the possibility of harmful side effects. Not all medications are suitable for this method of delivery, which is most effective with water-soluble drugs.

Because the process is not invasive and generates fewer negative reactions, there are immediately and obvious advantages. Liposomes are completely biodegradable, and contain no petroleum-derived compounds or other unwanted toxic substances. They easily survive an onslaught of powerful acid, and later function as mini time-release stations within the small intestine. Powerful cancer drugs administered in this way create less collateral damage to surrounding tissues.

While being used successfully today in many hospitals, there are some drawbacks. Production costs are comparatively high, but are subject to a natural decrease as product use expands. Seal leakage has been an issue in some cases, and simple oxidation processes can diminish effectiveness. Certain drugs may experience a diminished half-life, and their long-term viability may be reduced. Even with these known issues, positive benefits exceed negative reports.

The past several years witnessed a transition from mainly medical use to include internal delivery of nutritional supplements and even cosmetic substances
Because the process is not invasive and generates fewer negative reactions, there are immediately and obvious advantages. Liposomes are completely biodegradable, and contain no petroleum-derived compounds or other unwanted toxic substances. They easily survive an onslaught of powerful acid, and later function as mini time-release stations within the small intestine. Powerful cancer drugs administered in this way create less collateral damage to surrounding tissues.

While being used successfully today in many hospitals, there are some drawbacks. Production costs are comparatively high, but are subject to a natural decrease as product use expands. Seal leakage has been an issue in some cases, and simple oxidation processes can diminish effectiveness. Certain drugs may experience a diminished half-life, and their long-term viability may be reduced. Even with these known issues, positive benefits exceed negative reports.

The past several years witnessed a transition from mainly medical use to include internal delivery of nutritional supplements and even cosmetic substances. Anecdotal evidence abounds regarding the increased effectiveness of administering both vitamins and minerals in this manner. For years Vitamin C has enjoyed an enviable reputation for fighting upper respiratory viral infections, and encapsulated forms are thought to produce even better results.

Widespread information is available today regarding personal home encapsulation of vitamins, minerals, and herbal extracts. Producing high-quality encapsulated products is both costly and involved, and is not proven to effectively combat aging issues. As this effective method of physical drug delivery is improved and becomes more widespread, consumers will benefit most from its introduction to existing beneficial heal regimens.




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